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福泰制药Vertex Pharmaceuticals(VRTX)2025年第一季度业绩报告「NASDAQ」(英文版)(11页).pdf

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1、Vertex Reports First Quarter 2025 Financial ResultsMay 5,2025 Total revenue of$2.77 billion,a 3%increase compared to Q1 2024;raised the low end of total revenue guidance by$100 million to a new range of$11.85 to$12 billion Strong progress with CASGEVY,ALYFTREK and JOURNAVX launches Povetacicept(pove

2、)IgAN Phase 3 interim analysis(IA)cohort fully enrolled and zimislecel Phase 3 program to complete dosing this quarter,settingup potential filings in 2026;inaxaplin Phase 3 IA cohort on track to complete enrollment in the second half of 2025 Four programs already in pivotal development,with pivotal

3、study of pove in primary membranous nephropathy(pMN)to start this year BOSTON-(BUSINESS WIRE)-May 5,2025-Vertex Pharmaceuticals Incorporated(Nasdaq:VRTX)today reported consolidated financial results forthe first quarter ended March 31,2025,and raised the low end of its total revenue guidance range b

4、y$100 million,from$11.75 billion to$12 billion to anew range of$11.85 billion to$12 billion.“Vertex delivered a strong start to 2025 with notable execution across the business as we grow and diversify the revenue base,progress multiplelaunches and advance the R&D pipeline.We continued to expand our

5、leadership in CF and build global momentum for CASGEVY,and we launchedJOURNAVX in moderate-to-severe acute pain,”said Reshma Kewalramani,M.D.,Chief Executive Officer and President of Vertex.“With multipleprograms in pivotal development including povetacicept,which continues to make rapid progress in

6、 achieving its potential as a pipeline-in-a-product,and additional programs in early and mid-stage development,Vertex is poised to continue to deliver value for years to come.”First Quarter 2025 ResultsTotal revenue increased 3%to$2.77 billion compared to the first quarter of 2024,primarily driven b

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Vertex Pharmaceuticals Incorporated发布了2025年第一季度的财务报告。主要内容包括: 1. 总收入为27.7亿美元,较2024年同期增长3%,主要得益于TRIKAFTA/KAFTRIO和ALYFTREK的持续表现。 2. 研发费用为9.8亿美元,较2024年同期增长24%,主要原因是支持多个临床开发项目的持续研发投资。 3. 非GAAP净利润为11亿美元,较2024年同期下降8%,主要原因是运营费用的增加。 4. 2025年全年收入预期上调至118.5亿至120亿美元,非GAAP研发费用预计为4.9亿至5亿美元。 5. 主要产品包括治疗囊性纤维化、镰状细胞病和输血依赖性β地中海贫血的药物,以及治疗中重度急性疼痛的JOURNAVX。 6. 正在开发治疗1型糖尿病、APOL1介导的肾脏疾病、IgA肾病、原发性膜性肾病、常染色体显性多囊肾病和肌强直性营养不良1型的药物。
Vertex 2025年第一季度财报亮点有哪些? Vertex的CF产品组合有哪些新进展? Vertex在急性疼痛领域有哪些新动态?
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