WHYZE 健康.pdf

1、WHYZE HealthCan we transform RWE into actionable health outcomes?(in Ireland)Prof Frank Sullivan-CMO Co-Founder 6thFebruary 2025page2 2024 All Rights ReservedWhat is Real World EvidenceCentral role of clinical trials in healthcare improvementReal world data:Health information collated outside of cli

2、nical trialsWhat is an Actionable Health Outcome?Results that provide clear medical/personal decision-making utility.Providing specific actions for prevention/dx/txCentral role of data managementE.G.PSA,HbA1c leading to changes in lifestyle/testing etcpage3 2024 All Rights ReservedClinical Trial Res

3、ultsReal World OutcomesHandpicked patientsControlled EnvironmentNarrow timeframepage4 2024 All Rights ReservedBridging the Gap Between Clinical Trials and Real-World OutcomesHighly structuredLess structured?ActionableHigh patient numbersSampleVariability in AdministrationShort-Term observationsRelia

4、nt on data/SearchingExpensiveEHR regulations and existing deployment focusSelected cohortLess reliant on scientific tools for interpretation-BiostatisticsSmall patient numbersLong-Term EffectivenessError-prone,biasData siloing and fragmentationClinical TrialsReal World Evidencepage5 2024 All Rights

5、ReservedThe WHYZE ApproachWHYZE unifies data from patients,providers,and Life Science companies to transform Real-World Evidence(RWE)into real-world outcomes.Condition-specificEfficientAffordableReal World Evidence(RWE)To transform intoReal-world Outcomespage6 2024 All Rights ReservedUse CaseProstat

6、e Cancerpage7 2024 All Rights ReservedProstate CancerIn Irelandpage8 2024 All Rights ReservedProstate brachytherapy outcomes study(Blackrock Health)page9 2024 All Rights ReservedSurvival Curvepage10 2024 All Rights ReservedRisk Factors page11 2024 All Rights ReservedSimilarity Gradepage12 2024 All R