唐丽杰-2011年至今我国PEDV变异株与其他腹泻病毒共感染的分子流行病学调查与分析.pdf

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1、2 20 01 11 1年年至至今今我我国国P PE ED DV V变变异异株株与与其其他他腹腹泻泻病病毒毒共共感感染染的的分分子子流流行行病病学学调调查查与与分分析析唐丽杰 教授 博士生导师 Professor Tang Lijie PhD Advisor东北农业大学 Northeast Agricultural University2024年4月26日 April 26,2024Investigation of transmission and evolution of PEDV variants and co-infections in China over past decades一带

2、一路国际生猪产业大会仔猪腹泻概况 Introduction of diarrhea in piglets仔猪腹泻是引起仔猪生长受阻和仔猪高死亡率的重要原因,疾病的防治一直是一个引人注目的世界性问题。Diarrhea in piglets is an important disease causing growth restriction and high mortality,and its the prevention and treatment has always been a global issue.养猪人最恐惧的疫情之一。One of the most feared outbreak

3、s by pig farmers.3日龄以内仔猪感染死亡率可达100%，7日龄以内发病猪死亡率达50%80%。The mortality rate of piglets infected within 3 days of age can reach 100%,and the mortality rate of pigs infected within 7 days of age can reach 50%to 80%.猪腹泻病一直是困扰养猪业重要疫病，也是影响养猪业的重要疾病之一。Swine diarrhea has always been an important disease that

4、troubles the pig farming industry and is also one of the important diseases affecting the industry.2011年至今，猪腹泻病高发，PEDV单独感染及多病原混合感染在规模化养殖场流行，可能也与生猪养殖贸易的全球化有关，推动了新病原或新的变异病原出现和传播。Since 2011,there has been a high incidence of porcine diarrhea disease,with the prevalence of PEDV single infection and mixe

5、d infection of multiple pathogens in large-scale pig farms.This may also be related to the globalization of pig farming trade,which has promoted the emergence and spread of new or mutated pathogens.一带一路国际生猪产业大会病病毒毒名名称称S Sp pe ec ci ie es s种种类类g ge en no om me e科科属属F Fa am mi il ly y G Ge en nu us s有

6、有无无囊囊膜膜E En nv ve el lo op pe e我我国国首首次次报报道道年年份份F Fi ir rs st t r re ep po or rt te ed d i in n C Ch hi in na aC Cl li in ni ic ca al l s si ig gn ns s临临床床特特征征猪猪流流行行性性腹腹泻泻病病毒毒（P PE ED DV V）R RN NA A冠冠状状病病毒毒科科甲甲型型冠冠状状病病毒毒属属有有囊囊膜膜1 19 98 84 4年年呕呕吐吐、水水样样腹腹泻泻和和脱脱水水新新生生仔猪发发病病死死亡亡率率为为8 80 0%-1 10 00 0%V Vo