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再生元 JPM 2025 FINAL for Filing.pdf

上传人: c** 编号:603991 2025-02-03 41页 2.32MB

1、J.P.Morgan Healthcare ConferenceJ A N U A R Y 1 3,2 0 2 5This non-promotional presentation contains investigational data as well as forward-looking statements;actual results may vary materially.2Strategy&Business UpdateJ.P.M o r g a n H e a l t h c a r e C o n f e r e n c e 2 0 2 5Leonard S.Schleife

2、r,MD,PhD Co-Founder,Board Co-Chair,President&Chief Executive Officer3Note regarding forward-looking statementsThis presentation includes forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals,Inc.(Regeneron or

3、 the Company),and actual events or results may differ materially from these forward-looking statements.Words such as anticipate,expect,intend,plan,believe,seek,estimate,variations of such words,and similar expressions are intended to identify such forward-looking statements,although not all forward-

4、looking statements contain these identifying words.These statements concern,and these risks and uncertainties include,among others,the nature,timing,and possible success and therapeutic applications of products marketed or otherwise commercialized by Regeneron and/or its collaborators or licensees(c

5、ollectively,Regenerons Products)and product candidates being developed by Regeneron and/or its collaborators or licensees(collectively,Regenerons Product Candidates)and research and clinical programs now underway or planned,including without limitation EYLEA HD(aflibercept)Injection 8 mg,EYLEA(aflib

6、ercept)Injection,Dupixent(dupilumab)Injection,Libtayo(cemiplimab)Injection,Praluent(alirocumab)Injection,Kevzara(sarilumab)Injection,Evkeeza(evinacumab)Injection,Veopoz (pozelimab)Injection,Ordspono (odronextamab),itepekimab,fianlimab,garetosmab,linvoseltamab,Regenerons other oncology programs(inclu

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根据报告的内容,本文主要介绍了Regeneron Pharmaceuticals公司在2025年的战略和业务更新。主要内容包括: 1. Regeneron拥有4个“重磅炸弹”产品,包括EYLEA、Dupixent、Libtayo和Praluent,以及约40个具有重大商业潜力的产品候选者。 2. Dupixent现在全球治疗超过100万患者,2025年预计将增加新的适应症。EYLEA HD和EYLEA 2024年美国净销售额约为60亿美元。 3. Libtayo有望成为Regeneron的下一个内部发现的年销售额超过10亿美元的产品。 4. Regeneron正在开发多种新型药物,包括用于治疗COPD的itepekimab、用于治疗皮肤癌的fianlimab和用于治疗多发性骨髓瘤的linvoseltamab等。 5. Regeneron正在利用基因编辑技术开发基因疗法,包括用于治疗遗传性耳聋的DB-OTO和用于治疗重症肌无力的pozelimab+cemdisiran等。 6. Regeneron正在开发新型抗凝血药物REGN7508和REGN9933,用于预防血栓形成。 7. Regeneron正在开发新型减肥药物,包括与GLP-1类药物联合使用的trevogrumab和garetosmab等。 8. Regeneron正在开发新型过敏治疗方法,包括与Dupixent联合使用的linvoseltamab等。
再生元如何利用其技术平台开发新药? 再生元在哪些疾病领域有突破性进展? 再生元如何通过基因技术治疗遗传性疾病?
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