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Alnylam Presentation at JPMorgan 2023.pdf

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1、1 2023 Alnylam Pharmaceuticals,Inc.January 9,2023Yvonne Greenstreet,MBChB,MBAChief Executive Officer41stAnnual J.P.Morgan Healthcare ConferenceNathan(USA)Diagnosed with AHP2Alnylam Forward Looking StatementsThis presentation contains forward-looking statements within the meaning of Section 27A of th

2、e Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934.Allstatements other than historical statements of fact regarding Alnylams expectations,beliefs,goals,plans or prospects including,without limitation,expectations regarding Alnylamsaspiration to become a leading biotech c

3、ompany and the planned achievement of its“Alnylam P5x25”strategy,the potential for Alnylam to identify new potential drug developmentcandidates and advance its research and development programs,Alnylams ability to obtain approval for new commercial products or additional indications for its existing

4、 products,and Alnylams projected commercial and financial performance should be considered forward-looking statements.Actual results and future plans may differ materially from thoseindicated by these forward-looking statements as a result of various important risks,uncertainties and other factors,i

5、ncluding,without limitation:the direct or indirect impact of theCOVID-19 global pandemic or any future pandemic on our business,results of operations and financial condition and the effectiveness or timeliness of our efforts to mitigate the impactof the pandemic;the potential impact of the January 2

6、022 leadership transition on our ability to attract and retain talent and to successfully execute on our“Alnylam P5x25”strategy;the finalization and audit of our fourth quarter and 2022 fiscal year financial results,which could potentially result in changes or adjustments to the selected preliminary

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根据报告的内容,本文主要介绍了Alnylam公司的业务发展情况。Alnylam是一家专注于RNAi疗法的生物技术公司,其产品线包括ONPATTRO、AMVUTTRA、GIVLAARI和OXLUMO等,用于治疗罕见病和遗传病。2022年,Alnylam的净产品收入达到8.94亿美元,同比增长35%。Alnylam计划在2023年提交sNDA,以扩大ONPATTRO在ATTR淀粉样心肌病中的适应症。此外,Alnylam还计划开展多项临床试验,包括在CNS中首次进行RNAi治疗的人体试验。Alnylam的目标是在2025年前实现40%以上的收入复合年增长率,并在未来不需要额外的股权融资即可实现财务自给自足。
Alnylam如何成为领先的生物技术公司? 2023年Alnylam有哪些重要目标? Alnylam的RNAi疗法平台有何优势?
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