1、August 5,2025Q2 25 Earnings Call2Provided August 5,2025,as part of an oral presentation and is qualified by such,contains forward-looking statements,actual results may vary materially;Amgen disclaims any duty to update.Safe Harbor StatementThis presentation contains forward-looking statements that a

2、re based on the current expectations and beliefs of Amgen.All statements,other than statements of historical fact,are statements that could be deemed forward-lookingstatements,including any statements on the outcome,benefits and synergies of collaborations,or potential collaborations,with any other

3、company(including BeOne Medicines Ltd.or Kyowa Kirin Co.,Ltd.),the performance of Otezla(apremilast),our acquisitions of ChemoCentryx,Inc.or Horizon Therapeutics plc(including the prospective performance and outlook of Horizons business,performance and opportunities,and any potential strategic benef

4、its,synergies oropportunities expected as a result of such acquisition),as well as estimates of revenues,operating margins,capital expenditures,cash,other financial metrics,expected legal,arbitration,political,regulatory or clinical results or practices,customer and prescriber patterns or practices,

5、reimbursement activities and outcomes,effects of pandemics or other widespread health problems on our business,outcomes,progress,and other such estimates and results.Forward-lookingstatements involve significant risks and uncertainties,including those discussed below and more fully described in the

6、Securities and Exchange Commission(SEC)reports filed by Amgen,including our most recent annual report on Form 10-K and any subsequent periodic reports on Form 10-Q and current reports on Form 8-K.Unless otherwise noted,Amgen is providing this information as of the date of this presentation and does