1、S-1 1 tm2415719-14_s1.htm S-1TABLE OF CONTENTSAs filed with the Securities and Exchange Commission on May 23,2025.Registration No.333-UNITED STATESSECURITIES AND EXCHANGE COMMISSIONWashington,D.C.20549FORM S-1REGISTRATION STATEMENTUNDERTHE SECURITIES ACT OF 1933 CARIS LIFE SCIENCES,INC.(Exact name o

2、f registrant as specified in its charter)Texas 8071 85-2077369 (State or other jurisdiction ofincorporation or organization)(Primary Standard IndustrialClassification Code Number)(I.R.S.EmployerIdentification Number)750 W.John Carpenter FreewaySuite 800Irving,TX 75039Telephone:(866)771-8946(Address,

3、including zip code,and telephone number,including area code,of registrants principal executive offices)David D.HalbertFounder,Chairman,and Chief Executive OfficerCaris Life Sciences,Inc.750 W.John Carpenter Freeway,Suite 800Irving,TX 75039Telephone:(866)771-8946(Name,address,including zip code,and t

4、elephone number,including area code,of agent for service)Copies to:Nathan AjiashviliAlison HaggertySamer ZabanehLatham&Watkins LLP1271 Avenue of the AmericasNew York,NY 10020Telephone:(212)906-1200 J.Russel DentonGinger AppleberryMichael R.SullivanCaris Life Sciences,Inc.750 W.John Carpenter Freeway

5、,Suite 800Irving,TX 75039Telephone:(866)771-8946 Eric BlanchardDivakar GuptaCharles S.KimCooley LLP500 Boylston StreetBoston,MA 02116Telephone:(617)937-2300 Approximate date of commencement of proposed sale to the public:As soon as practicable after the effective date of this registration statement.

6、If any of the securities being registered on this Form are to be offered on a delayed or continuous basis pursuant to Rule 415 under the Securities Actof 1933,check the following box.If this Form is filed to register additional securities for an offering pursuant to Rule 462(b)under the Securities A