1、Understanding the Use of Medicines in the U.S.2025Evolving Standards of Care,Patient Access,and SpendingAPRIL202 5The use of medicines in the U.S.has grown significantly as more patients receive treatment for chronic diseases and new novel treatments become available.However,patients still face sign

2、ificant barriers to accessing medicines,including through limitations of their insurance coverage and the high costs of newer therapies.Early impacts of the Inflation Reduction Act have provided some cost savings to patients and will likely continue to drive increased savings as other aspects are ph

3、ased in.Aggregate growth in spending on medicines has accelerated as more patients are prescribed novel medicines and standards of care begin to shift.This annual trend report is part of a continued effort to advance our collective knowledge by providing evidence-based research,which can help establ

4、ish a common foundation for discussion and understanding by all stakeholders.It is intended to contribute to the advancement of health in a system that remains highly fragmented and opaque.Areas of focus in this years report range from looking at how medicine usage patterns have shifted,to the impac

5、t of out-of-pocket costs and benefit designs on patients,to the complex nature of drug pricing.Dynamics that have become apparent during 2024 have driven significant revisions to the outlook,and in this report the drivers of change in medicine spending over the next five years are deconstructed to e

6、nable better understanding.This examination includes the impact of novel obesity and diabetes medicines which have been significant drivers of growth,and the uptake of other novel medicines expanding into new patient populations and becoming established as backbone therapies.This study was produced