史记署-用传代细胞培养出来的安全和有效的非洲猪瘟弱毒疫苗.pdf

1、Development of a Safe and Efficacious Live Attenuated Virus ASF Vaccine Using Cell Passage Technology利利用用细细胞胞传传代代技技术术研研制制安安全全有有效效的的A AS SF F减减毒毒活活疫疫苗苗Jishu Shi史史记记署署Professor of Vaccine Immunology疫苗免疫学教授Dr.Wayne and Hilda Appleton Endowed ProfessorDr.Wayne and Hilda Appleton 教授Director,Biologics Dev

2、elopment Module生物制品开发模块总监Director,Center on Biologics Development and Evaluation生物制品开发和评价中心总监Director,U.S.-China Center for Animal Health美中动物卫生中心主任College of Veterinary Medicine兽医学院Kansas State University,Manhattan,Kansas,USA美国堪萨斯州曼哈顿堪萨斯州立大学Center on Biologics 生生物物制制品品中中心心 Development&Evaluation开开发发

3、和和评评估估一带一路国际生猪产业大会Presentation Outline汇汇报报大大纲纲My experience with experimental ASF vaccines我我使使用用实实验验性性A AS SF F疫疫苗苗的的经经验验VNUA-ASF-LAV 2 and VNUA-ASF-LAV3V VN NU UA A-A AS SF F-L LA AV V 2 2和和V VN NU UA A-A AS SP P-L LA AV V3 3Safety Evaluation安全性评估Efficacy Evaluation功效评估Analysis of Protective Immuni

4、ty 保护性免疫分析 一带一路国际生猪产业大会32023 Beijing International ASF Workshop2 20 02 23 3年年北北京京国国际际A AS SF F研研讨讨会会ASF a serious transboundary animal disease with the potential for rapid international spreadA AS SF F是是一一种种严严重重的的跨跨界界动动物物疾疾病病，有有可可能能在在国国际际上上迅迅速速传传播播。Global distribution of ASF,2005-2023.2 20 00 05 5-2

5、 20 02 23 3年年A AS SF F的的全全球球分分布布。Map based on data from OIE World Animal Health Information system(https:/www.oie.int/wahis_2/public/wahid.php/Diseaseinformation/Diseaseoutbreakmaps?)and Global Disease Monitoring Reports(https:/www.swinehealth.org/global-disease-surveillance-reports/).Names of count

6、ries with ASF are given in the map.地图基于世界动物卫生组织（OIE）世界动物卫生信息系统（https：/www.oie.int/wahis_2/public/wahid.php/Diseaseinformation/Diseaseoutbreakmaps？）和全球猪病监测报告（https：/www.swinehealth.org/global-disease-surveillance-reports/）的数据。地图中给出了存在ASF的国家名称。ASF is active in 40 countries around the worldA AS SF F活活跃