更年期：这关乎女性健康而不仅仅是女性科技.pptx

1、Menopause:Its about FemHealth,not just FemTech,Michael N.Liebman,PhDSasha Rieders,MScIPQ Analytics,LLC(Kennett Square,PA)in collaboration with 23Strands(Sydney,Australia),IPQs Womens Health Program(Development and Disease),Conception-natural,newborn,Full TermBirth,Pre TermBirth,InfantToddler,child,a

2、dolescent,adult,28 days,23 mos,11 years,18 years,IVF,Pre-eclampsia,Hypertensive Disorders of Pregnancy,Premature Birth,BronchopulmonaryDysplasia,Developmental Issues,Rare Diseases,Breast Cancer,Multiple Sclerosis,Peri-menopause/Menopause,Underserved Populations,Infant/MaternalMorbidity/Mortality,Nor

3、mal/abnormalDevelopment,Cardiovascular Disease,Infectious Diseases,Postpartum Conditions,Perimenopause is a Process,Not a Symptom,Margaret Hamburg,FDA,clinicians have long observed that patients with similar symptomsmay have different illnesses”Paving the Way for Personalized Medicine 2013,Hot Flash

4、es,Headaches,Frequent urination,Headaches,Female Developmental Landmarks,Menarche,Child-bearing,Peri-menopause,Menopause,CumulativeDevelopment,Lactation,Fetal Development,Processes and Pathways,Protein Expression,Gene Expression,1Ridge stage Less than 5mm embryo2 Milk hill stage More than 5.5-mm emb

5、ryo3Mammary disc stage Around 1011mm embryo4 lobule type stage 11.025.0-mm embryo5Cone stage 2530-mm embryo6Budding stage 3068-mm embryo7 Indentation stage 68-mm to 10 cm8Branching stage 10 cm fetus9 Canalization stage20 and 32 weeks of gestation10 End-vesicle stage,in which the end vesicles arecomp

6、osed of a monolayer of epithelium and containcolostrumsNewborn,Conception,-Breast Cancer-Cardiovascular Disease-Osteoporosis-.,Post-MenopausalDisease Risk,Gestational AgeWeight gainHDPsGestational DiabetesDelivery MethodBreast FeedingPregna