1、Landscape analysis of Amyotrophic Lateral S2ContentsIntroduction3Methodology3Global ALS drug distribution analysis4Phase wise distribution analysis(2009-2023)4Marketed drugs5Approved drugs6Drugs in preregistration phase6Drugs under late-stage clinical development7Drugs under early-stage clinical dev

2、elopment9Major players in the clinical development of ALS drugs16Drug development landscape for ALS16Diagnostic Agents for ALS17Upcoming treatments for ALS17Major players in the overall market25Target trend analysis for overall drug profiles26Drug classes in focus for ALS therapeutics27Agreements fo

3、r ALS drugs27Conclusion30References31Landscape analysis of Amyotrophic Lateral Sclerosis IntroductionAmyotrophic lateral sclerosis(ALS),also known as Lou Gehrigs Disease,is a rare neurological disease that affects motor neuronsthose nerve cells in the brain and spinal cord that control voluntary mus

4、cle movement.As motor neurons degenerate and die,they stop sending messages to the muscles,which causes the muscles to weaken,start to twitch(fasciculations),and waste away(atrophy).Eventually,the brain loses its ability to initiate and control voluntary movements.Some of the symptoms involved with

5、the disease include muscle twitching and cramps,tight and stiff muscles(spasticity)with weakness affecting an arm,a leg,the neck,or diaphragm and slurred/nasal speech.The patients may also develop problems with language or decision-making along with dementia over time.Stages of ALSThere are 4 stages

6、 in ALS:Stage 1-The Beginning-The muscles will become softer,appear to be weaker,or sometimes,they become tight and spastic.Stage 2-The Middle-The muscles of the affected areas will become paralyzed,and other muscles will seem stiff as if they were about to become paralyzed as well.Stage 3-The Late