1、Annual Report Why is access tohealthcare soimportant?Life-changing innovation is only meaningful if it reaches those who need it.We put access at the core of our business and consider it a key part of our commitment toimproving patient outcomes.Our combined strengths indiagnostics and pharmaceutical

2、s position us to play adecisive role along the patients journey.We partner withstakeholders to address the root causes at global,country and community levels that prevent access to innovative healthcare,no matter where people live.Shareholder letters 4Business performance 18Reporting and strategy 28

3、 Diagnostics 38 Pharmaceuticals 54 Personalised healthcare 70 Access to healthcare 84 People and culture 98 Environment 114 Community engagement 130 Business ethics 144 Corporate Governance 158 Remuneration Report more than 125 years,Roche has worked to improve thehealth of countless people all over

4、 the world.Withthetrust of our shareholders and guided by scientificprogress,we will continue to identify and seizeopportunities well into the future.Letters to shareholdersIn his final letter to shareholders,Christoph Franz reflects onthe companys performance in 2022 and the countless collaboration

5、s we have with partners around the world toincrease access to healthcare for everyone.Chairman Basel,SwitzerlandDr Christoph FranzFor the last time as CEO,Severin Schwan shares his thoughts on the progress we have made for patients and society and our advances in digital healthcare.CEO Roche Group B

6、asel,SwitzerlandDr Severin SchwanLetters to shareholders|Roche 7Dr Christoph Franz8Dear ShareholdersYour company achieved good results even in last years challenging environment.Sales increased by 2%*and net income amounted to 13.5billionSwissfrancs.The Board of Directors proposes at the Annual Gene