1、Recognizing the value of next-generation sequencing and call-to-action for its quality assurance and standardization.Unlocking the Value of QualityNext-Generation Sequencingin APACContents03 1 Contents02Unlocking the value of quality next-generation sequencing in APAC 04Unlocking the value of qualit

2、y next-generation sequencing in APAC 06Unlocking the value of quality next-generation sequencing in APAC 08Unlocking the value of quality next-generation sequencing in APAC 010Unlocking the value of quality next-generation sequencing in APAC 12Unlocking the value of quality next-generation sequencin

3、g in APAC 14Unlocking the value of quality next-generation sequencing in APAC 16Unlocking the value of quality next-generation sequencing in APAC 18Unlocking the value of quality next-generation sequencing in APAC 20Unlocking the value of quality next-generation sequencing in APAC Lack of standardiz

4、ation and quality in molecular testing procedures in APACNo consistency on how laboratories performing NGS tests are regulatedChallenge:In a large survey carried out by the IASLC,lack of quality and standardization was the second most frequent barrier for molecular testing in patients with lung canc

5、er in Asia after cost.57 Lack of standardization and quality can be further split into three aspects of NGS:processing of sample from patients,bioinformatic analysis of results and reporting of results.Processing of sample from patients:For instance,in the case of tissue samples,this included insuff

6、icient amount of tumor cells for testing(81%),inadequate tissue quality(52%),lack of sensitivity of assay or assay use failure(22%),and inadequate technical expertise in the laboratory(12%).Indeed,this study showed that 22Unlocking the value of quality next-generation sequencing in APAC 24Unlocking