Sindhu Ravishankar（快速通道城市研究所华盛顿特区）.pdf

1、Tracking Progress:Are We on Track to Achieve the US HIV Incidence Targets?Sindhu Ravishankar,MPhil Vice President,Global Health Strategy IAPAC and Fast-Track Cities InstitutePresentation Overview Progress towards US HIV Incidence Targets Decrease new infections nationally by 75%2025 and 90%by 2030(N

2、ational HIV/AIDS Strategy 2022-2025)Incidence Prevalence Ratio a potentially useful tool to benchmark incidence progress Service Disruptions and Impacts threats to current and future progress Future Steps Data source:NCHHSTP AtlasPlus 15%reduction for all EHE jurisdictions 4040-50%reduction:50%reduc

3、tion:6 jurisdictions 2020-40%reduction40%reduction:16 jurisdictions 0 0-20%reduction:20%reduction:18 jurisdictions 0 0-20%increase:20%increase:10 jurisdictions Benchmarking Using the Incidence Prevalence RatioThe incidence-prevalence ratio(IPR)is a proposed benchmark for HIV epidemic control Relevan

4、ce:Provides a comprehensive view of the epidemics dynamics allowing health authorities can assess the rate of new infections relative to the overall number of people living with HIV.This comparison helps monitor the effectiveness of HIV prevention efforts and HIV treatment interventions.Defines a co

5、ntrol threshold:If a newly infected person survives D years post-infection,the IPR threshold=1/D.*Interpretation:When there are 1 new HIV infection per PLHIV over a lifetime,the epidemic declines.Proposed Calculation of IPR Threshold:D=life-expectancy post-diagnosis+national average time to diagnosi

6、s IPR threshold=1/D IPR Trends for EHE Jurisdictions (2017-2022)Calculation of IPR Threshold for the US:In the US Life-expectancy post diagnosis=32.85 years;average time to diagnosis=3.33 years IPR threshold=1/(32.85+3.33)=0.028 Jurisdictions under IPR.028 have reached epidemic control based on IPR